Alcohol “directly causes some types of cancer,” doctors warn

Oxford, England (StudyFinds.org) – If you enjoy a glass of wine or beer every night, one study may make you think twice the next time you need to remove the edge. A new study warns that alcohol consumption can be attributed to the development of multiple types of cancer.

In addition, a study from the University of Oxford shows that people who have never taken or only drink occasionally are 31% less likely to develop certain types of illness.

alcohol Associated with various tumors Includes breast, intestine, mouth, throat and liver. Scientists now show that it is a deadly trigger, especially for people with certain genetic mutations.

“These findings show that alcohol directly causes several types of cancer,” said Dr. Becky Im, Principal Researcher at Oxford Population Health. statement.. “These risks can be even higher in people with hereditary low-alcohol tolerance who are unable to properly metabolize alcohol.”

The author says the risk was greatest Participants who drank regularly Despite being susceptible.

Genes are important

The British team has tracked more than 150,000 men and women in China for an average of 11 years. Alcohol claims to kill about 3 million people worldwide each year. This is the life of more than 400,000 people from cancer. Consumption is increasing, especially in developing countries.

However, it was difficult to rule out confounding factors, Smoking, dieting, etc., It can produce biased results. It was also unclear whether alcohol causes other forms such as lung and stomach cancer.

In collaboration with Chinese experts, Dr. Im and colleagues used a new approach by investigating two variants associated with low-alcohol intake. The genes known as ALDH2 and ADH1B are common in Chinese and East Asian populations, but rare in Europeans. They fuel a carcinogenic compound called acetaldehyde in the blood, resulting in an unpleasant “flushing” sensation.Mutation was used as a surrogate For drinking.. They are inherited at birth regardless of other lifestyle factors.

Men with one or two copies of ADH1B were 13 to 25 percent less likely to develop cancer. This phenomenon was especially true for alcohol-related tumors, especially head, neck and esophageal tumors.

Men who had two copies of ALDH2 drank very little.They had 31 percent Low risk of cancer Of the esophagus, colon, rectum and liver. It also reduced the risk of developing cancer by 14%.

Since women rarely drink alcohol in China, the main analysis focused on men, one-third of whom were indulged most of the week. Those who had one and took it regularly had a significantly higher risk of head and neck cancer and esophageal cancer.

Reducing alcohol consumption is an easy way to reduce your risk of cancer

For those who completely abstain Or a person who drinks occasionallyThere was no overall association between carrying one copy of ALDH2 and increased cancer risk. The results remained the same when considering smoking, diet, physical activity, weight, and family history of cancer.

Only 2% of women drank regularly, and mutations were not associated with an increased risk of cancer. This indicates that the lower risk of male carriers is due to their lower alcohol consumption.

Result is, International Journal of Cancer, Add to evidence Refraining from alcohol is the healthiest option..

“Our research emphasizes the need to lower the population level of alcohol consumption to prevent cancer,” says Dr. Iona Milwood, also a senior researcher at Oxford.

South West News Service writer Mark Waghorn contributed to this report.

Alcohol “directly causes some types of cancer,” doctors warn

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